Description

2-Chloro-11-Methyl-5H-Benzo[E]Pyrimido[5,4-B][1,4]Diazepin-6(11H)-One is a high-purity, heterocyclic organic compound with a complex fused-ring structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the development of novel pharmacologically active molecules, particularly within the benzodiazepine and pyrimidine chemical space. This compound is essential for research and development laboratories in the pharmaceutical and agrochemical sectors, where it is used to synthesize new active ingredients and explore structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies in organic synthesis and medicinal chemistry at universities and CROs.
• Material Science Precursor: Potential intermediate for creating specialized organic electronic materials or ligands for catalysis.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing production processes for target molecules.

Basic Information

Product Name	2-Chloro-11-Methyl-5H-Benzo[E]Pyrimido[5,4-B][1,4]Diazepin-6(11H)-One
CAS No.	66427-86-9
Molecular Formula	C₁₄H₁₀ClN₃O
Molecular Weight	271.70 g/mol
Synonyms	2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one; 2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one; 66427-86-9; Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 2-chloro-11-methyl-; 2-Chloro-11-methyl-5H-dibenzo[b,e][1,4]diazepin-6-one (related core structure name)
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-11-Methyl-5H-Benzo[E]Pyrimido[5,4-B][1,4]Diazepin-6(11H)-One adheres to stringent in-process controls and final batch testing to ensure consistent purity and identity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization. Certificates of Analysis (COA) detailing purity, impurities, and full spectroscopic data are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.