Description

N*1*-Benzyl-4-Trifluoromethyl-Benzene-1,2-Diamine is a high-purity aromatic diamine derivative featuring a benzyl and a trifluoromethyl substituent, making it a versatile and valuable chemical intermediate. This compound is critical for introducing both amine functionality and fluorine-containing groups into complex molecular architectures, which can significantly alter physical and biological properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by material scientists for advanced polymer applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the presence of the trifluoromethyl group which enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, polyimides, and epoxy resins, imparting enhanced thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex heterocycles and functionalized aromatic compounds via reactions such as condensation and cyclization.
• Dye and Pigment Intermediate: Utilized in the development of specialized colorants and imaging agents where the diamine structure is integral to chromophore formation.

Basic Information

Product Name	N*1*-Benzyl-4-Trifluoromethyl-Benzene-1,2-Diamine
CAS No.	66315-44-4
Molecular Formula	C₁₄H₁₃F₃N₂
Molecular Weight	266.26 g/mol
Synonyms	1-Benzyl-4-(trifluoromethyl)benzene-1,2-diamine; N1-Benzyl-4-(trifluoromethyl)-1,2-benzenediamine; 2-Amino-N-benzyl-5-(trifluoromethyl)aniline; 4-(Trifluoromethyl)-1,2-phenylenediamine, N-benzyl derivative; 1,2-Benzenediamine, N1-benzyl-4-(trifluoromethyl)-; N-Benzyl-4-trifluoromethyl-o-phenylenediamine; BTFBDA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our N*1*-Benzyl-4-Trifluoromethyl-Benzene-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For customers with specific regulatory needs, we can support documentation for cGMP, ISO, or other quality standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged operations to minimize oxidation risk. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.