Description

S-Methyl-D-Cys-Oh is a high-purity, non-proteinogenic amino acid derivative featuring a methylated thioether side chain. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in protease inhibitor research.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce modified cysteine residues, altering stability, bioavailability, and receptor binding.
• Bioconjugation & Linker Chemistry: Serves as a precursor for creating specialized linkers in antibody-drug conjugates (ADCs) and other bioconjugation platforms.
• Biochemical Research: Employed as a standard or reagent in metabolic pathway studies and enzyme inhibition assays.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective synthesis for complex organic molecules.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing sulfur-containing flavor compounds, subject to appropriate regulatory approvals.

Basic Information

Product Name	S-Methyl-D-Cys-Oh
CAS No.	66255-16-1
Molecular Formula	C4H9NO2S
Molecular Weight	135.18 g/mol
Synonyms	(R)-2-Amino-3-(methylthio)propanoic acid; D-2-Amino-3-(methylthio)propionic acid; D-S-Methylcysteine; (R)-S-Methylcysteine; D-3-(Methylthio)alanine; Methyl-D-cysteine; (R)-3-(Methylthio)alanine; D-Methylcysteine
EINECS	Contact for details

Quality Control

Our S-Methyl-D-Cys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.