Description

n-Butyl-2-Chloropyrimidin-4-Amine is a versatile pyrimidine derivative, a key building block in advanced organic synthesis. Its molecular structure makes it a critical intermediate for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production in pharmaceutical, agrochemical, and fine chemical industries seeking to create novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the pyrimidine core provides key biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems used in cross-coupling and other synthetic transformations.
• Material Science Research: A valuable monomer or precursor for developing polymers and advanced materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Used to develop molecular probes for studying biological processes and enzyme functions in research settings.

Basic Information

Item	Details
Product Name	n-Butyl-2-Chloropyrimidin-4-Amine
CAS No.	66229-56-9
Molecular Formula	C8H12ClN3
Molecular Weight	185.65 g/mol
Synonyms	2-Chloro-N-butylpyrimidin-4-amine; 4-Amino-2-chloro-N-butylpyrimidine; 2-Chloro-4-(butylamino)pyrimidine; N-Butyl-2-chloro-4-pyrimidinamine; 2-Chloro-4-(n-butylamino)pyrimidine; 4-(Butylamino)-2-chloropyrimidine; 2-Chloro-4-butylaminopyrimidine; N-Butyl-2-chloropyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our n-Butyl-2-Chloropyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.