Description

Argipressin, (3,4-Dehydro-Pro)(7)- is a synthetic analog of the neurohypophysial hormone vasopressin, characterized by a specific dehydroproline modification at position 7. This structural alteration is significant for research into peptide stability, receptor binding affinity, and the development of novel therapeutic agents targeting vasopressin pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in endocrinology, cardiovascular research, and the development of peptide-based diagnostics or therapeutics.

Application

• Pharmaceutical Research & Development: As a key reference standard and active ingredient in preclinical studies for vasopressin receptor (V1a, V1b, V2) modulation.
• Biochemical Research: Investigation of peptide hormone structure-activity relationships (SAR), metabolic stability, and degradation pathways.
• Endocrinology Studies: Used in vitro and in vivo models to study the role of vasopressin in blood pressure regulation, fluid balance, and central nervous system functions.
• Diagnostic Development: Potential use in the development of immunoassays or as a labeled compound for tracing vasopressin pathways.
• Peptide Chemistry: Serves as a model compound for studying the synthesis, purification, and analysis of modified peptides containing non-standard amino acids.

Basic Information

Product Name	Argipressin, (3,4-Dehydro-Pro)(7)-
CAS No.	66185-31-7
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	[Dehydroproline7]-Vasopressin; [3,4-Dehydro-Pro7]-Argipressin; 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-4-L-threonine-8-L-arginine-9-desglycine-[3,4-dehydro-L-proline7]-vasopressin; (3,4-Dehydro-Pro7)-Vasopressin; [δPro7]-AVP; Dehydroproline7-Arginine Vasopressin
EINECS	Contact for details

Quality Control

Our Argipressin, (3,4-Dehydro-Pro)(7)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis to ensure structural integrity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.