Description

N(8)-2-Carboxyethylspermidine is a specialized, high-purity spermidine derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a crucial intermediate and reference standard for studying polyamine metabolism, cellular processes, and enzyme interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and manufacturers of fine chemicals and diagnostic reagents seeking reliable, high-quality building blocks for innovative applications.

Application

• Biochemical Research: Used as a key intermediate and substrate in enzymatic studies, particularly for spermidine/spermine N1-acetyltransferase (SSAT) and other polyamine-metabolizing enzymes.
• Pharmaceutical Development: Serves as a precursor or reference compound in the synthesis and discovery of novel therapeutics targeting polyamine pathways, which are implicated in cell growth, proliferation, and certain disease states.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and components for diagnostic assays and kits that measure polyamine levels or related enzymatic activity.
• Life Science Tools: Integrated into the development of specialized reagents, inhibitors, or probes for cellular and molecular biology research focused on autophagy, aging, and stress response.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the custom synthesis of more complex polyamine analogs and conjugates for specialized research applications.

Basic Information

Product Name	N(8)-2-Carboxyethylspermidine
CAS No.	66165-34-2
Molecular Formula	C11H24N4O2
Molecular Weight	244.33 g/mol
Synonyms	N8-(2-Carboxyethyl)spermidine; N8-(3-Carboxypropyl)spermidine (tautomer); 2-Carboxyethylspermidine; N1,N4-Bis(3-aminopropyl)butane-1,4-diamine, N8-carboxyethyl derivative; Spermidine, N-(2-carboxyethyl)-; 3-[(4-aminobutyl)amino]propyl-3-aminopropanoic acid; Polyamine derivative CAS 66165-34-2
EINECS	Contact for details

Quality Control

Our N(8)-2-Carboxyethylspermidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) documenting the specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.