Description

His-Leu-Gly-Leu-Ala-Arg is a synthetic hexapeptide composed of the amino acids Histidine, Leucine, Glycine, Leucine, Alanine, and Arginine. This sequence-specific peptide is of significant interest for research and development in biochemistry and pharmaceutical sciences. It serves as a critical building block or model compound for studying protein-protein interactions, enzyme substrates, and peptide-based therapeutics. Professionals in biotechnology, pharmaceutical R&D, and academic research require this high-purity peptide for advanced experimental applications.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic studies and proteomics research.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery and synthesis of novel peptide-based drugs.
• Protease/Enzyme Studies: Acts as a specific sequence for investigating enzyme kinetics, inhibition, and specificity of proteases like trypsin or other serine proteases.
• Cell Biology: Employed in studies of cell signaling pathways, receptor binding, and intracellular transport mechanisms.
• Antigen Synthesis: Can be utilized for generating antibodies or in immunoassay development for specific epitope mapping.
• Academic & Institutional Research: Provides a defined peptide sequence for teaching and fundamental research in universities and institutes.

Basic Information

Item	Details
Product Name	His-Leu-Gly-Leu-Ala-Arg
CAS No.	66157-45-7
Molecular Formula	C29H52N12O8
Molecular Weight	696.80 g/mol
Synonyms	H-L-H-L-G-L-A-R-OH; Histidyl-Leucyl-Glycyl-Leucyl-Alanyl-Arginine; Hexapeptide (His-Leu-Gly-Leu-Ala-Arg); HLGLAR; L-Histidyl-L-leucyl-glycyl-L-leucyl-L-alanyl-L-arginine; Peptide 66157-45-7; Arg-Ala-Leu-Gly-Leu-His (reverse sequence)
EINECS	Contact for details

Quality Control

Our His-Leu-Gly-Leu-Ala-Arg is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the product should be handled in a low-humidity environment and desiccated for long-term storage. For optimal stability, keep the container sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.