Description

Acetylmuramyl-Valylisoglutamine is a synthetic muramyl dipeptide (MDP) derivative, a key structural component of bacterial peptidoglycan. This compound is of significant interest for its role as a potent immunomodulator and adjuvant, capable of stimulating both innate and adaptive immune responses. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for vaccine development, immunotherapy research, and as a reference standard in analytical studies.

Application

• Immunological Adjuvant Research: A key component in the study and development of novel vaccine adjuvants to enhance immune response.
• Vaccine Development: Used in preclinical and formulation research for next-generation bacterial and viral vaccines.
• Immunostimulant Studies: Employed in vitro and in vivo to investigate mechanisms of innate immunity and macrophage activation.
• Pharmaceutical Intermediates: Serves as a critical building block or active ingredient in the synthesis of advanced immunotherapeutic agents.
• Reference Standard: Provides a high-purity standard for quality control (QC) and analytical method development in pharmaceutical laboratories.
• Biochemical Research: Used to study NOD2 receptor signaling pathways and inflammatory responses.

Basic Information

Product Name	Acetylmuramyl-Valylisoglutamine
CAS No.	66112-56-9
Molecular Formula	C22H38N4O11
Molecular Weight	534.56 g/mol
Synonyms	N-Acetylmuramyl-L-valyl-D-isoglutamine; MDP; Muramyl Dipeptide; Ac-MDP; L-Valyl-D-isoglutamine N-acetylmuramyl; N-Acetylmuramyl-L-Val-D-isoGln; Adjuvant Peptide; Immunoadjuvant Peptide; 6-O-[(R)-2-[(S)-2-[[(2R)-2-[(1S)-1-Carboxy-2-methylpropyl]amino]-2-carboxyethyl]amino]-3-methylbutanoyl]amino]-2-[(3R,5R,6S)-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-2-oxoethyl]acetamide
EINECS	Contact for details

Quality Control

Our Acetylmuramyl-Valylisoglutamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.