Description

N(4)-Acetylspermidine is a specific acetylated derivative of the polyamine spermidine, playing a significant role in cellular metabolism and biochemical research. This compound is valued for its utility as a key biochemical standard and research reagent in the study of polyamine pathways, which are critical in cell growth, proliferation, and differentiation. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on metabolic studies, biomarker discovery, and the development of novel therapeutic agents.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in analytical laboratories for the quantification and study of polyamine metabolism.
• Metabolic Pathway Analysis: Essential for in vitro and in vivo studies investigating the acetylation and deacetylation cycles of spermidine and related polyamines.
• Biomarker Development: Serves as a critical compound in the development of diagnostic assays for diseases where polyamine levels are dysregulated.
• Pharmaceutical R&D: Employed in drug discovery programs targeting enzymes like spermidine/spermine N1-acetyltransferase (SSAT) for potential oncology and neurology applications.
• Cell Culture & Life Sciences: Used as a supplement or modulator in specialized cell culture media to study its effects on cellular processes like autophagy and apoptosis.
• Academic Research: A key reagent for universities and research institutes conducting fundamental studies in biochemistry, molecular biology, and aging research.

Basic Information

Product Name	N(4)-Acetylspermidine
CAS No.	66039-56-3
Molecular Formula	C9H21N3O
Molecular Weight	187.28 g/mol
Synonyms	N1-Acetylspermidine; N-Acetylspermidine; 1-Acetylspermidine; N(1)-Acetylspermidine; N-Acetyl-1,4-diaminobutane; N-(4-Aminobutyl)acetamide; Spermidine, N1-acetyl-; N1-Acetylspermidine dihydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our N(4)-Acetylspermidine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.