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N(Alpha)-Formyltetragastrin CAS NO 66025-31-8


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CAS No.:66025-31-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N(Alpha)-Formyltetragastrin is a synthetic, chemically modified derivative of the gastrin peptide, designed for enhanced stability and specific research applications. This compound is a critical tool for investigating gastrointestinal physiology and hormone-receptor interactions in a controlled laboratory setting. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biochemical suppliers focused on endocrinology and digestive system studies.

Application

  • Biochemical Research: A key reagent for studying the structure-activity relationship (SAR) of gastrin and cholecystokinin (CCK) peptides.
  • Pharmacological Studies: Used in in vitro and in vivo models to investigate gastric acid secretion and mucosal growth mechanisms.
  • Receptor Binding Assays: Serves as a ligand or competitor in assays targeting the cholecystokinin B (CCKB) / gastrin receptor.
  • Peptide Chemistry Standard: Acts as a reference standard in analytical methods (HPLC, MS) for peptide purity and identity confirmation.
  • Drug Discovery: Used in high-throughput screening (HTS) platforms to identify novel therapeutics for gastrointestinal disorders.

Basic Information

Product Name N(Alpha)-Formyltetragastrin
CAS No. 66025-31-8
Molecular Formula C33H49N7O9S
Molecular Weight 719.85 g/mol
Synonyms Formyltetragastrin; N-Formyltetragastrin; Boc-βAla-Trp-Met-Asp-Phe-NH2 (Formyl); Nα-Formyltetragastrin; Gastrin I (1-4) Formyl Derivative; (N-Formyl)-β-Ala-Trp-Met-Asp-Phe-NH2; FG; For-Tetragastrin
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Quality Control

Our N(Alpha)-Formyltetragastrin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research-grade standards and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content (Amino Acid Analysis) ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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