Description

4-Pyrimidinemethanamine, α-Methyl-, (S)- (9Ci) is a chiral, non-racemic pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-value chiral building block, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for metal-catalyzed asymmetric synthesis, enhancing enantioselectivity in critical bond-forming reactions.
• Agrochemical Research: Serves as a building block for creating new, stereochemically-defined active ingredients for crop protection products.
• Academic & Institutional Research: Employed in methodological studies and the synthesis of complex natural products or molecular probes in university and corporate R&D labs.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing organizations (CMOs) for producing high-value, specialty chemicals on a laboratory to pilot scale.

Basic Information

Product Name	4-Pyrimidinemethanamine, α-Methyl-, (S)- (9Ci)
CAS No.	66007-69-0
Molecular Formula	C6H9N3
Molecular Weight	123.16 g/mol
Synonyms	(S)-α-Methyl-4-pyridinemethanamine; (S)-1-(Pyrimidin-4-yl)ethan-1-amine; (S)-1-(4-Pyrimidinyl)ethylamine; (S)-4-(1-Aminoethyl)pyrimidine; (S)-α-Methyl-4-pyrimidinemethylamine; (S)-4-(1-Aminoethyl)pyrimidine; (S)-1-(4-Pyrimidyl)ethylamine; (S)-4-(1-Aminoethyl)pyridine (common misnomer)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identity confirmation. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.