Description

Oxytocin, Asp(5)- CAS NO 65907-78-0 is a synthetic analogue of the neuropeptide hormone oxytocin, specifically modified at the fifth amino acid position. This structural modification is critical for research into receptor binding specificity and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neuroendocrinology, reproductive health, and behavioral science.

Application

• Pharmacological Research: Used as a reference standard and tool compound for studying oxytocin receptor (OXTR) interactions, signaling pathways, and structure-activity relationships (SAR).
• Drug Discovery: Serves as a key intermediate or lead compound in the development of new therapeutics targeting social behavior disorders, anxiety, and postpartum depression.
• Biochemical Assays: Employed in competitive binding assays, ELISA development, and other in vitro diagnostic tests to quantify oxytocin-like activity.
• Neuroscience Studies: Fundamental for investigating the role of oxytocin variants in neural circuits related to social bonding, trust, and stress response.
• Peptide Chemistry: Acts as a model compound for studying peptide stability, formulation, and delivery methods due to its specific amino acid substitution.

Basic Information

Product Name	Oxytocin, Asp(5)- CAS NO 65907-78-0
CAS No.	65907-78-0
Molecular Formula	C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	1-{(4R,7S,10S,13S,16S,19R)-19-Amino-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-10-[(2S)-1-(carboxymethylamino)-1-oxobutan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}-N-(carbamoylmethyl)-N-methyl-L-asparaginamide; Aspartocin; [Asp⁵]-Oxytocin; 5-Aspartic Acid Oxytocin; Oxytocin (5-L-Aspartic acid)
EINECS	Contact for details

Quality Control

Our Oxytocin, Asp(5)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.