Description

6-(tert-Butoxy)-5-Fluorohexahydro-2,4-Dioxo-5-Pyrimidinecarboxylic Acid is a high-value, fluorinated pyrimidine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both a tert-butoxy protecting group and a fluorine atom on the pyrimidine ring, makes it an essential building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex molecules with potential therapeutic or pesticidal activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated nucleoside analogs and other potential antiviral or anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluoropyrimidine core imparts desirable biological activity and stability.
• Chemical Synthesis: Serves as a versatile intermediate for introducing fluorinated heterocyclic structures into more complex molecules in medicinal and process chemistry.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new chemical entities and reaction pathways involving protected, fluorinated uracil derivatives.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for client projects.

Basic Information

Product Name	6-(tert-Butoxy)-5-Fluorohexahydro-2,4-Dioxo-5-Pyrimidinecarboxylic Acid
CAS No.	65906-29-8
Molecular Formula	C9H13FN2O5
Molecular Weight	248.21 g/mol
Synonyms	5-Fluoro-6-(tert-butoxy)hexahydro-2,4-dioxo-5-pyrimidinecarboxylic acid; 5-Fluoro-6-(tert-butoxy)-1,3-diazinane-2,4-dione-5-carboxylic acid; 5-Carboxy-5-fluoro-6-(tert-butoxy)hexahydropyrimidine-2,4-dione; tert-Butyl 5-fluoro-2,4-dioxo-1,3-diazinane-5-carboxylate (tautomeric form); 5-Fluoro-6-(tert-butoxy)dihydro-2,4(1H,3H)-pyrimidinedione-5-carboxylic acid; 65906-29-8; Fluorinated tert-butoxy pyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 6-(tert-Butoxy)-5-Fluorohexahydro-2,4-Dioxo-5-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.