Description

5-[(2,4-Diamino-5-Pyrimidinyl)Methyl]-3-Methoxy-2(1H)-Pyridinone is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique molecular structure, featuring both pyrimidine and pyridinone rings, makes it an invaluable intermediate for synthesizing novel therapeutic agents. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the discovery of new drugs, particularly in areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Antifolate Drug Research: Used in the synthesis of potential dihydrofolate reductase (DHFR) inhibitors for antimicrobial and anticancer applications.
• Biochemical Research: Serves as a standard or reagent in enzymatic and receptor-binding studies due to its specific structure.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing complex heterocyclic libraries for high-throughput screening.
• Reference Standard: Utilized as an analytical reference standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-[(2,4-Diamino-5-Pyrimidinyl)Methyl]-3-Methoxy-2(1H)-Pyridinone
CAS No.	65873-76-9
Molecular Formula	C11H12N6O2
Molecular Weight	260.25 g/mol
Synonyms	3-Methoxy-5-[(2,4-diamino-5-pyrimidinyl)methyl]-2(1H)-pyridinone; 5-[(2,4-Diamino-5-pyrimidinyl)methyl]-3-methoxy-1H-pyridin-2-one; 2(1H)-Pyridinone, 5-[(2,4-diamino-5-pyrimidinyl)methyl]-3-methoxy-; NSC 339638; 65873-76-9; 5-[(2,4-Diamino-5-pyrimidinyl)methyl]-3-methoxy-2-pyridinone
EINECS	Contact for details

Quality Control

Our 5-[(2,4-Diamino-5-Pyrimidinyl)Methyl]-3-Methoxy-2(1H)-Pyridinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.