Description

Morpholine, 4-(4-((2-(2-Chlorophenyl)-6-Methyl-4-Pyrimidinyl)Amino)Ben Zoyl)-, Monohydrochloride is a high-purity, specialized organic compound primarily used as a key pharmaceutical intermediate. This compound is critical for the synthesis of advanced active pharmaceutical ingredients (APIs) due to its specific molecular architecture. It is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical industries seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic structures.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the research, development, and scale-up production of specific APIs, leveraging its morpholine and pyrimidine functional groups.
• Biochemical Research: Serves as a reagent or reference standard in life science research for studying biological pathways and target interactions.
• Fine Chemical Production: Employed in the manufacture of other high-value, complex specialty chemicals requiring precise molecular assembly.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Morpholine, 4-(4-((2-(2-Chlorophenyl)-6-Methyl-4-Pyrimidinyl)Amino)Ben Zoyl)-, Monohydrochloride
CAS No.	65789-87-9
Molecular Formula	C22H22ClN4O2 • HCl
Molecular Weight	443.80 g/mol (Free base: 407.89 g/mol)
Synonyms	4-[4-[[2-(2-Chlorophenyl)-6-methyl-4-pyrimidinyl]amino]benzoyl]morpholine hydrochloride; 4-(4-((2-(2-Chlorophenyl)-6-methylpyrimidin-4-yl)amino)benzoyl)morpholine monohydrochloride; N-[4-(Morpholine-4-carbonyl)phenyl]-2-(2-chlorophenyl)-6-methylpyrimidin-4-amine hydrochloride; 65789-87-9; UNII-8F4Q8X4Q4H; 8F4Q8X4Q4H; CHEMBL3186470; BDBM50121273
EINECS	Contact for details

Quality Control

Our Morpholine, 4-(4-((2-(2-Chlorophenyl)-6-Methyl-4-Pyrimidinyl)Amino)Ben Zoyl)-, Monohydrochloride is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and specifications can be aligned with client-specific pharmacopeial or internal requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions if opened, to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.