Description

6-Chloro-N-methylpyrimidin-4-amine is a versatile pyrimidine derivative, a crucial nitrogen-containing heterocyclic building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing more complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and kinase inhibitors.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic compounds, enabling structure-activity relationship (SAR) studies.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers and functional materials with specific electronic or binding properties.
• Biochemical Research: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and molecular probes for biological studies.

Basic Information

Product Name	6-Chloro-N-methylpyrimidin-4-amine
CAS No.	65766-32-7
Molecular Formula	C5H6ClN3
Molecular Weight	143.57 g/mol
Synonyms	4-Amino-6-chloro-N-methylpyrimidine; 6-Chloro-4-(methylamino)pyrimidine; 6-Chloro-N-methyl-4-pyrimidinamine; 4-Pyrimidinamine, 6-chloro-N-methyl-; 6-Chloro-4-methylaminopyrimidine; N-Methyl-6-chloropyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 6-Chloro-N-methylpyrimidin-4-amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reliable quality for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.