Description

1-(4-Chloro-Phenyl)-2,2,2-Trifluoro-Ethylamine is a versatile fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a chlorophenyl ring and a trifluoroethylamine moiety, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial building block in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Used in the design and synthesis of specialized ligands for catalysis and molecular recognition applications.
• Material Science Research: Employed as a monomer or modifier in the synthesis of specialty polymers and advanced materials with unique surface or electronic properties.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on introducing fluorine into complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	1-(4-Chloro-Phenyl)-2,2,2-Trifluoro-Ethylamine
CAS No.	65686-86-4
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	4-Chloro-α-(trifluoromethyl)benzylamine; 1-(4-Chlorophenyl)-2,2,2-trifluoroethanamine; 2,2,2-Trifluoro-1-(4-chlorophenyl)ethylamine; α-(Trifluoromethyl)-4-chlorobenzylamine; 4-Chloro-α,α,α-trifluoromethylbenzylamine; 1-(4-Chlorophenyl)-2,2,2-trifluoroethylamine; p-Chloro-α-(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Phenyl)-2,2,2-Trifluoro-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.