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Vasopressin, 1-Deamino-2-Phe-7-(3,4-Dehydro)Pro-8-Arg- CAS NO 65647-64-5
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CAS No.:65647-64-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Vasopressin, 1-Deamino-2-Phe-7-(3,4-Dehydro)Pro-8-Arg- is a synthetic analog of the endogenous neurohypophysial hormone arginine vasopressin, designed for enhanced pharmacological stability and receptor selectivity. This high-purity peptide is critical for research and development in endocrinology and cardiovascular physiology, offering a reliable tool for studying vasoconstriction, water retention, and central nervous system functions. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and advanced biotech companies developing novel therapeutic agents and diagnostic assays.
Application
- Pharmacological Research: Used as a reference standard and active agent in studies investigating vasopressin receptor (V1a, V2) signaling pathways and physiological responses.
- Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis of novel peptide-based therapeutics targeting conditions like diabetes insipidus, septic shock, and bleeding disorders.
- Biochemical Assays: Employed in enzyme-linked immunosorbent assays (ELISAs), radioimmunoassays (RIAs), and other in vitro diagnostic tests for hormone level quantification.
- Academic & Clinical Studies: Facilitates fundamental research into the role of vasopressin analogs in memory, social behavior, stress response, and autonomic regulation.
- Quality Control & Standardization: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating purity in pharmaceutical manufacturing.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Vasopressin, 1-Deamino-2-Phe-7-(3,4-Dehydro)Pro-8-Arg- |
| CAS No. | 65647-64-5 |
| Molecular Formula | C46H65N13O12S2 |
| Molecular Weight | 1040.2 g/mol |
| Synonyms | Desmopressin Impurity F; [1-Deamino, 2-Phenylalanine, 7-(3,4-Dehydroproline), 8-Arginine]vasopressin; 1-Deamino-2-Phe-7-(δ3,4-Pro)-8-Arg-Vasopressin; dDAVP Related Compound F; Deamino-Dicarba Vasopressin Analog; (3-Mercaptopropionic acid)-Phe-(3,4-dehydro-Pro)-Arg-vasopressin; ADH analog |
| EINECS | Contact for details |
Quality Control
Every batch of our Vasopressin, 1-Deamino-2-Phe-7-(3,4-Dehydro)Pro-8-Arg- is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Single Impurity (HPLC) | ≤ 2.0% |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80.0% |
| Acetate Content (HPLC) | ≤ 15.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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