Description

1,2,3,4-Tetrahydro-4-(3-Dimethylaminopropyl)-1-Phenyl-5H-1,4-Benzodiazepin-5-One CAS NO 65647-12-3 is a high-purity benzodiazepine derivative, a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in providing a reliable and scalable building block for the research and development of novel therapeutic agents. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new central nervous system (CNS) active compounds and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the design, synthesis, and screening of new drug candidates targeting CNS receptors.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Item	Details
Product Name	1,2,3,4-Tetrahydro-4-(3-Dimethylaminopropyl)-1-Phenyl-5H-1,4-Benzodiazepin-5-One
CAS No.	65647-12-3
Molecular Formula	C20H23N3O
Molecular Weight	321.42 g/mol
Synonyms	4-(3-Dimethylaminopropyl)-1-phenyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one; 1-Phenyl-4-(3-dimethylaminopropyl)-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one; Benzodiazepine Derivative 65647-12-3; 1,4-Benzodiazepin-5-one, 1,2,3,4-tetrahydro-4-(3-(dimethylamino)propyl)-1-phenyl-; 4-(3-Dimethylaminopropyl)-1-phenyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-one
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-4-(3-Dimethylaminopropyl)-1-Phenyl-5H-1,4-Benzodiazepin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.