Description

Ethyl 2-(5-Bromopyrimidin-2-Yl)-2-Cyanoacetate is a high-value brominated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture for developing novel active compounds. It is primarily utilized by the pharmaceutical and agrochemical industries for the research and development of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex molecules for potential therapeutic applications, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyclization reactions to construct diverse heterocyclic systems.
• Material Science Research: Investigated as a precursor for organic electronic materials and ligands for catalytic systems.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Ethyl 2-(5-Bromopyrimidin-2-Yl)-2-Cyanoacetate
CAS No.	65364-66-1
Molecular Formula	C9H8BrN3O2
Molecular Weight	270.08 g/mol
Synonyms	Ethyl (5-bromopyrimidin-2-yl)cyanoacetate; 2-Cyano-2-(5-bromopyrimidin-2-yl)acetic acid ethyl ester; Ethyl α-cyano-α-(5-bromopyrimidin-2-yl)acetate; Acetic acid, 2-cyano-2-(5-bromopyrimidin-2-yl)-, ethyl ester; 65364-66-1; 5-Bromo-2-pyrimidinylcyanoacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Bromopyrimidin-2-Yl)-2-Cyanoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.