Description

3-(4-Fluorophenoxy)Benzyl Bromide CAS NO 65295-58-1 is a high-purity organic bromide building block characterized by its fluorinated phenoxy and benzyl bromide functional groups. This compound is critical for facilitating efficient carbon-carbon bond formation and molecular diversification in advanced synthetic workflows. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the fluorophenoxy moiety for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or functional agents for advanced polymers and liquid crystals.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-(4-Fluorophenoxy)Benzyl Bromide
CAS No.	65295-58-1
Molecular Formula	C13H10BrFO
Molecular Weight	281.12 g/mol
Synonyms	1-(Bromomethyl)-3-(4-fluorophenoxy)benzene; (3-(4-Fluorophenoxy)phenyl)methyl bromide; α-Bromo-3-(p-fluorophenoxy)toluene; 3-(p-Fluorophenoxy)benzyl bromide; 3-(4-Fluorophenoxy)-α-bromotoluene; Benzene, 1-(bromomethyl)-3-(4-fluorophenoxy)-; 3-(4-Fluorophenoxy)benzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Fluorophenoxy)Benzyl Bromide is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.