Description

Isoleucinomycin is a naturally occurring, cyclic depsipeptide antibiotic belonging to the valinomycin family. This compound is valued for its potent ionophoric properties, specifically its high selectivity and affinity for transporting potassium ions across biological membranes. It serves as a critical research tool in biochemistry and microbiology for studying ion transport mechanisms and membrane potential. Key industries that utilize this specialty biochemical include pharmaceutical research, agrochemical development, and advanced material science.

Application

• Biochemical Research: As a model ionophore for studying potassium ion (K+) transport, channel function, and membrane biophysics in vitro.
• Antimicrobial Studies: Investigation of its antibiotic activity against Gram-positive bacteria and related structure-activity relationships.
• Membrane Potential Probes: Used in experiments to deliberately alter or collapse membrane potentials in cells, organelles, and synthetic vesicles.
• Pharmaceutical Development: A reference compound for the design and screening of novel ionophoric antibiotics and therapeutics.
• Agricultural Research: Exploration of its potential as a lead compound for developing new crop protection agents.
• Sensor Technology: A component in the development of ion-selective electrodes and biosensors for potassium detection.

Basic Information

Product Name	Isoleucinomycin
CAS No.	65230-09-3
Molecular Formula	C54H90N6O18
Molecular Weight	1087.3 g/mol
Synonyms	Isoleucinomycin; Antibiotic 6016; NSC 326230; Cyclo[L-Val-D-Hyi-D-Val-L-Lac-L-Ile-D-Hyi-D-Val-L-Lac-] (cyclic depsipeptide structure); Valinomycin analogue; Potassium ionophore I; 6016 Antibiotic
EINECS	Contact for details

Quality Control

Our Isoleucinomycin is produced and tested under strict quality management protocols. Each batch is characterized to ensure identity, purity, and biological activity suitable for research applications. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC purity assay, spectroscopic identification (NMR, IR, MS), and specific rotation measurements. We adhere to cGMP principles for research-grade biochemicals to guarantee reproducibility and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, keep containers under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Potassium Ionophoric Activity	Confirmed by assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.