Description

2(1H)-Pyrimidinone, 4-Amino-5-Ethynyl- (9Ci) is a specialized heterocyclic organic compound featuring a pyrimidinone core functionalized with amino and ethynyl groups. This unique structure makes it a valuable key intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis Building Block: The reactive amino and ethynyl groups enable diverse coupling reactions (e.g., Sonogashira, click chemistry) for constructing complex molecular architectures.
• Material Science Research: Serves as a monomer or functional unit in the development of specialty polymers and advanced organic electronic materials.
• Bioconjugation Chemistry: The ethynyl group is utilized for site-specific labeling and modification of biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Basic Information

Product Name	2(1H)-Pyrimidinone, 4-Amino-5-Ethynyl- (9Ci)
CAS No.	65223-79-2
Molecular Formula	C6H5N3O
Molecular Weight	135.12 g/mol
Synonyms	4-Amino-5-ethynylpyrimidin-2(1H)-one; 4-Amino-5-ethynyl-2(1H)-pyrimidinone; 5-Ethynyl-4-aminopyrimidin-2(1H)-one; 4-Amino-5-ethynyl-1H-pyrimidin-2-one; 4-Amino-5-ethynyl-1,2-dihydropyrimidin-2-one; 5-Ethynyl-4-aminouracil (common name); 4-Amino-5-ethynyluracil
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Pyrimidinone, 4-Amino-5-Ethynyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. All materials are characterized by modern analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.