Description

Butanoic Acid, 2-Amino-3-Oxo-, (S)- (9Ci) is a chiral, non-proteinogenic amino acid derivative with a ketone functional group. This compound is of significant interest in organic synthesis and pharmaceutical research, serving as a versatile chiral building block for the development of active pharmaceutical ingredients (APIs) and complex molecules. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, particularly for drugs targeting metabolic and neurological pathways.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Biochemical Research: Employed in studies of enzyme mechanisms and metabolic pathways involving amino acid analogs.
• Peptidomimetics Development: Incorporated into peptide chains to create modified peptides with enhanced stability or biological activity.
• Ligand Synthesis: Serves as a precursor for chelating agents and chiral ligands used in metal catalysis.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Butanoic Acid, 2-Amino-3-Oxo-, (S)- (9Ci)
CAS No.	65116-81-6
Molecular Formula	C₄H₇NO₃
Molecular Weight	117.10 g/mol
Synonyms	(S)-2-Amino-3-oxobutanoic acid; L-2-Amino-3-oxobutanoic acid; (S)-2-Aminoacetoacetic acid; 2-Amino-3-oxobutyric acid, (S)-; 3-Oxo-L-2-aminobutanoic acid; Aminooxobutyric acid; Acetoaminic acid; 65116-81-6
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 2-Amino-3-Oxo-, (S)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.