Description

Dnp-Pro-Gln-Gly-Oh CAS NO 65080-33-3 is a specialized, protected peptide derivative featuring a dinitrophenyl (Dnp) group. This compound is a critical synthetic intermediate in advanced peptide chemistry and biochemical research, valued for its role in selective protection and deprotection strategies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers involved in the synthesis of complex peptides and peptidomimetics.

Application

• Peptide Synthesis Intermediate: Serves as a key building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Biochemical Research: Used in studies of enzyme-substrate interactions and the development of protease inhibitors.
• Pharmaceutical Development: Employed in the research and development of novel therapeutic peptides and drug candidates.
• Protecting Group Chemistry: The Dnp group is utilized for the temporary protection of amino functionalities during multi-step synthetic sequences.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Dnp-Pro-Gln-Gly-Oh
CAS No.	65080-33-3
Molecular Formula	C19H24N6O8
Molecular Weight	464.43 g/mol
Synonyms	N-2,4-Dinitrophenyl-L-prolyl-L-glutaminyl-glycine; DNP-Pro-Gln-Gly-OH; (2S)-1-[(2,4-Dinitrophenyl)amino]-1-oxopropan-2-yl]amino]-4-[[(1S)-1-carboxy-2-(carbamoylamino)ethyl]amino]-4-oxobutanoic acid; N-Dnp-L-prolyl-L-glutaminylglycine; Dnp-Pro-Gln-Gly; L-Proline, N-(2,4-dinitrophenyl)-, L-glutaminylglycine deriv.
EINECS	Contact for details

Quality Control

Our Dnp-Pro-Gln-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.