Description

Lidamidine Hydrochloride CAS NO 65009-35-0 is a synthetic pharmaceutical compound primarily recognized for its antidiarrheal properties. It functions as an α-2 adrenergic receptor agonist, offering a targeted mechanism of action for gastrointestinal regulation. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry developing formulations for the management of acute and chronic diarrhea. Its reliable performance makes it a critical component for producing effective gastrointestinal therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription antidiarrheal medications.
• Gastrointestinal Therapeutics: Formulation into tablets, capsules, or oral solutions for treating acute and chronic diarrhea.
• Clinical Research: Utilization as a reference standard or investigational compound in pharmacological studies related to gut motility and secretion.
• Veterinary Medicine: Potential application in veterinary formulations for managing diarrhea in animals.
• Bulk Pharmaceutical Manufacturing: Sourcing by contract manufacturing organizations (CMOs) for large-scale production of finished dosage forms.
• Analytical Development: Serves as a high-purity standard for method development and quality control testing in analytical laboratories.

Basic Information

Product Name	Lidamidine Hydrochloride
CAS No.	65009-35-0
Molecular Formula	C17H23N3O2 • HCl
Molecular Weight	329.85 g/mol (Free base: 293.38 g/mol)
Synonyms	Lidamidine HCl; N-(2,6-Dimethylphenyl)-N'-[imino(methylamino)methyl]urea monohydrochloride; 1-(2,6-Dimethylphenyl)-3-[imino(methylamino)methyl]urea hydrochloride; McN-JR-7904-23; McNJR-7904-23; WHR-1142A; Antidiarrheal Agent WHR-1142A
EINECS	Contact for details

Quality Control

Our Lidamidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and IR spectroscopy. We provide full traceability and support regulatory submissions. A Certificate of Analysis (COA) detailing all test results against relevant specifications is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Microbial Enumeration	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.