Description

Pyrimidine, 4-Chloro-2-(Chloromethyl)-6-Methyl- is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both a chloromethyl and a chloro substituent on the pyrimidine ring, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers and functional materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Dye & Pigment Industry: Intermediate for the production of specialized heterocyclic dyes and colorants.
• Custom Synthesis: A foundational substrate for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis projects.

Basic Information

Product Name	Pyrimidine, 4-Chloro-2-(Chloromethyl)-6-Methyl-
CAS No.	64994-45-2
Molecular Formula	C6H6Cl2N2
Molecular Weight	177.03 g/mol
Synonyms	4-Chloro-2-(chloromethyl)-6-methylpyrimidine; 2-(Chloromethyl)-4-chloro-6-methylpyrimidine; 6-Methyl-2-chloromethyl-4-chloropyrimidine; 4-Chloro-6-methyl-2-pyrimidinylmethyl chloride; NSC 403796
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Chloromethyl)-6-Methylpyrimidine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.