Description

L-Tyr-L-Ala-D-Ala-L-Phe-L-Met-Oh is a synthetic pentapeptide sequence of significant interest in biochemical and pharmaceutical research. This compound, with CAS number 64963-21-9, serves as a crucial building block and model substrate for studying enzyme kinetics, peptide stability, and receptor-ligand interactions. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in advanced peptide synthesis and metabolic pathway analysis.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics and enzyme inhibitors.
• Biochemical Assay Development: Employed as a specific substrate for studying the activity and specificity of proteolytic enzymes like peptidases and proteases.
• Metabolic Studies: Used in research to investigate peptide absorption, degradation pathways, and metabolic stability in biological systems.
• Academic Research: Serves as a tool compound in university and institutional labs for teaching and investigating principles of peptide chemistry and molecular biology.
• Quality Control & Analytical Standards: Acts as a high-purity reference material for calibrating analytical equipment (HPLC, MS) and validating analytical methods within quality control laboratories.

Basic Information

Product Name	L-Tyr-L-Ala-D-Ala-L-Phe-L-Met-Oh
CAS No.	64963-21-9
Molecular Formula	C30H40N6O7S
Molecular Weight	628.74 g/mol
Synonyms	Tyr-Ala-Ala-Phe-Met-OH; YAAFM-OH; L-Tyrosyl-L-alanyl-D-alanyl-L-phenylalanyl-L-methionine; Pentapeptide YAAFM; H-Tyr-Ala-Ala-Phe-Met-OH; 64963-21-9; N-(N-(N-(N-(N-L-Tyrosyl-L-alanyl)-D-alanyl)-L-phenylalanyl)-L-methionine)
EINECS	Contact for details

Quality Control

Our L-Tyr-L-Ala-D-Ala-L-Phe-L-Met-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.