Description

3-Hydroxyornithine is a non-proteinogenic amino acid derivative of ornithine, featuring an additional hydroxyl group on the β-carbon. This structural modification makes it a valuable chiral building block and intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from metabolic pathway studies to the development of novel therapeutics and diagnostics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and production of peptide-based drugs, enzyme inhibitors, and other bioactive compounds.
• Biochemical Research: Used as a standard or reagent in metabolic studies, particularly those investigating the urea cycle, polyamine biosynthesis, and amino acid metabolism.
• Nutritional Science: Investigated for its potential role in specialized nutritional formulations and metabolic supplements.
• Fine Chemical Synthesis: Employed in organic synthesis for introducing the 3-hydroxyornithine moiety into more complex molecular architectures.
• Diagnostic Reagent Development: Utilized in the formulation of assay kits and reagents for clinical diagnostics and research.

Basic Information

Product Name	3-Hydroxyornithine
CAS No.	64818-17-3
Molecular Formula	C5H12N2O3
Molecular Weight	148.16 g/mol
Synonyms	(2S,3S)-2,5-Diamino-3-hydroxypentanoic acid; L-3-Hydroxyornithine; (S,S)-3-Hydroxyornithine; 3-Hydroxy-L-ornithine; 2,5-Diamino-3-hydroxypentanoic acid; H-Orn(3-OH)-OH; 3-HO-Orn
EINECS	Contact for details

Quality Control

Our 3-Hydroxyornithine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets high-purity research and pharmaceutical intermediate standards. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.