Description

Methyl Pyroglutamyl-Histidyl-Pipecolate CAS NO 64783-97-7 is a synthetic peptide derivative of interest in advanced biochemical research and development. This compound is valued for its potential role in modulating specific biological pathways and its utility as a key intermediate in peptide synthesis. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries for developing novel therapeutic agents and bioactive ingredients.

Application

• Pharmaceutical Research: Serves as a critical intermediate or reference standard in the development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Studies: Used as a tool compound in academic and industrial research to investigate enzyme interactions, receptor binding, and cellular signaling pathways.
• Cosmetic & Dermatology: Explored for potential applications in advanced skincare formulations targeting specific skin conditions or anti-aging mechanisms.
• Process Development: Employed in process chemistry for scaling up peptide synthesis and optimizing manufacturing protocols.
• Diagnostic Reagents: Potential use in the development of specialized diagnostic kits and assays for clinical research.

Basic Information

Product Name	Methyl Pyroglutamyl-Histidyl-Pipecolate
CAS No.	64783-97-7
Molecular Formula	C17H25N5O5
Molecular Weight	379.41 g/mol
Synonyms	Methyl L-pyroglutamyl-L-histidyl-L-pipecolate; L-Pyroglutamyl-L-histidyl-L-pipecolic acid methyl ester; pGlu-His-Pip-OMe; Methyl Ester of pGlu-His-Pip; 5-Oxo-L-prolyl-L-histidyl-L-pipecolic acid methyl ester; (S)-Methyl 1-((S)-2-((S)-5-oxo-2-pyrrolidinecarboxamido)-3-(1H-imidazol-4-yl)propanamido)piperidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl Pyroglutamyl-Histidyl-Pipecolate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and comprehensive identification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.