Description

Alanine, β-[3-3H(N)] is a high-specific-activity tritium-labeled amino acid derivative, essential for advanced biochemical and pharmacological research. This radiolabeled compound provides a critical tool for tracing metabolic pathways, studying protein synthesis, and investigating amino acid transport mechanisms with high sensitivity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic developers engaged in cutting-edge tracer studies and drug discovery programs.

Application

• Metabolic Pathway Tracing: Used as a radiotracer to study the metabolism and fate of alanine and related compounds in biological systems.
• Protein Synthesis & Turnover Studies: Employed in pulse-chase experiments to investigate the kinetics of protein synthesis, degradation, and folding.
• Membrane Transport Research: Applied in assays to characterize and quantify amino acid transporter activity and kinetics across cell membranes.
• Pharmacokinetics & Drug Metabolism (ADME): Serves as a tool in preclinical studies to understand the absorption, distribution, metabolism, and excretion of new chemical entities.
• Biomedical Imaging Agent Development: Acts as a precursor or reference standard in the development of novel positron emission tomography (PET) or single-photon emission computed tomography (SPECT) imaging agents.
• Enzyme Mechanism Studies: Utilized to elucidate the mechanisms of enzymes that act on alanine, such as transaminases and racemases.

Basic Information

Product Name	Alanine, β-[3-3H(N)]
CAS No.	64700-13-6
Molecular Formula	C₃H₇NO₂ (³H-labeled)
Molecular Weight	~90.1 g/mol (³H-labeled)
Synonyms	3-Amino[3-³H]propanoic Acid; β-Alanine-3-³H; (R,S)-3-Amino[3-³H]propionic Acid; 3-Tritio-β-alanine; β-³H-Alanine; NSC 206315-³H; Abufene-³H; β-Aminopropionic Acid-³H
EINECS	Contact for details

Quality Control

Every batch of Alanine, β-[3-3H(N)] is manufactured and analyzed under strict quality systems to ensure exceptional radiochemical purity and specific activity. Comprehensive testing includes radiochemical purity by HPLC, specific activity determination, and confirmation of chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical parameters to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original packaging. The product is light-sensitive and should be handled in a manner that minimizes exposure. Users must follow all applicable laboratory safety and radiation protection protocols.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	Contact for details (Ci/mmol)
Chemical Purity (HPLC)	≥ 98%
Solvent	Ethanol:Water mixture (specified on COA)
Concentration	1 mCi/mL (Nominal)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.