Description

H-Gln-Gly-Pro-Oh Tfa is a protected tripeptide derivative, specifically the trifluoroacetate salt of Glutamine-Glycine-Proline. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), offering a protected side chain for glutamine to prevent unwanted side reactions. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the development of therapeutic peptides, bioactive probes, and complex peptidomimetics.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of therapeutic peptides targeting various diseases.
• Biochemical Research: Used as a standard or reagent in studying peptide structure, function, and metabolism.
• Cosmeceutical Peptide Synthesis: Building block for creating anti-aging or skin-repair peptide sequences.
• Academic & Institutional R&D: Essential for laboratories focused on peptide chemistry and drug discovery projects.
• Process Development: Serves as a reference standard for scaling up GMP-grade peptide API production.
• Diagnostic Reagent Manufacturing: Can be incorporated into peptide-based assay components and biomarkers.

Basic Information

Product Name	H-Gln-Gly-Pro-Oh Tfa
CAS No.	64642-59-7
Molecular Formula	C15H23N5O7 • C2HF3O2
Molecular Weight	529.42 g/mol
Synonyms	H-Gln-Gly-Pro-OH trifluoroacetate; Gln-Gly-Pro; Glutaminyl-glycyl-proline TFA salt; QGP-OH TFA; Fmoc-Gln(Trt)-Gly-Pro-OH (precursor related); N-(tert-Butoxycarbonyl)-L-glutaminyl-glycyl-L-proline (Boc related); L-Glutamine, N-L-glycyl-L-prolyl-, trifluoroacetate (1:1); Peptide Synthesis Building Block QGP
EINECS	Contact for details

Quality Control

Our H-Gln-Gly-Pro-Oh Tfa is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.