Description

4-Ala-Secretin CAS NO 64610-22-6 is a synthetic peptide analog of the gastrointestinal hormone secretin, specifically modified at the fourth amino acid position with alanine. This modification is designed to enhance its stability and biological activity profile for research and development applications. It is a critical reagent for pharmaceutical R&D, particularly in studies related to pancreatic function, gastrointestinal disorders, and metabolic research. The compound is essential for scientists and manufacturers in the biotechnology and pharmaceutical sectors requiring high-purity peptide intermediates.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the development of novel therapeutic agents targeting secretin receptors.
• Biochemical Assays: Serves as a critical ligand in receptor binding studies and functional assays to understand secretin signaling pathways.
• Metabolic Disorder Studies: Employed in preclinical research investigating pancreatic secretion, bicarbonate production, and related metabolic functions.
• Gastrointestinal Physiology Research: A vital tool for academic and industrial labs studying the role of secretin in digestion and gut health.
• Peptide Chemistry & Synthesis: Acts as a building block or model compound for advanced peptide synthesis and structure-activity relationship (SAR) studies.
• Diagnostic Development: Potential use in the development of diagnostic kits or assays for conditions related to secretin dysfunction.

Basic Information

Product Name	4-Ala-Secretin
CAS No.	64610-22-6
Molecular Formula	C130H220N44O41
Molecular Weight	3055.4 g/mol
Synonyms	Secretin (4-Ala); [Ala4]-Secretin; 4-Alanine Secretin; H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2; Alanyl4-Secretin; Secretin, 4-Ala-; Synthetic Secretin Analog
EINECS	Contact for details

Quality Control

Our 4-Ala-Secretin is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.