Description

4-Amino-1-(5-Oxooxolan-2-Yl)Pyrimidin-2-One is a high-purity heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and building block in medicinal chemistry. Its unique fused-ring structure containing both pyrimidinone and lactone moieties makes it a versatile precursor for the synthesis of complex, biologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of novel antiviral compounds targeting viral polymerases and replication mechanisms.
• Oncology Therapeutics: Serves as a precursor in the synthesis of potential chemotherapeutic agents and targeted cancer therapies.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and biochemical assays.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis for clients.

Basic Information

Product Name	4-Amino-1-(5-Oxooxolan-2-Yl)Pyrimidin-2-One
CAS No.	64567-41-5
Molecular Formula	C8H9N3O3
Molecular Weight	195.18 g/mol
Synonyms	4-Amino-1-(tetrahydro-2-oxo-3-furanyl)-2(1H)-pyrimidinone; 4-Amino-1-(5-oxotetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2(1H)-Pyrimidinone, 4-amino-1-(tetrahydro-2-oxo-3-furanyl)-; 4-Amino-1-(5-oxooxolan-2-yl)-1,2-dihydropyrimidin-2-one; 4-Amino-1-(5-oxotetrahydrofuran-2-yl)-1,2-dihydropyrimidin-2-one; 4-Amino-1-(γ-lactonyl)uracil; 4-Amino-1-(dihydro-5-oxo-2-furanyl)-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 4-Amino-1-(5-Oxooxolan-2-Yl)Pyrimidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical development and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.