Description

4'-Fluoro-3'-Methyl-[1,1'-Biphenyl]-4-Ol is a high-purity biphenyl derivative, specifically a fluorinated and methylated phenol, with the CAS registry number 64465-60-7. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, valued for its unique substitution pattern that enables precise molecular modifications. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal material industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal Materials: Serves as a core structural unit in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport or host materials in OLED device fabrication.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Material Science Research: Employed in academic and industrial labs to develop novel polymers and organic semiconductors with tailored electronic properties.

Basic Information

Product Name	4'-Fluoro-3'-Methyl-[1,1'-Biphenyl]-4-Ol
CAS No.	64465-60-7
Molecular Formula	C₁₃H₁₁FO
Molecular Weight	202.22 g/mol
Synonyms	[1,1'-Biphenyl]-4-ol, 4'-fluoro-3'-methyl-; 4-(4-Fluoro-3-methylphenyl)phenol; 3'-Methyl-4'-fluorobiphenyl-4-ol; 4-Hydroxy-4'-fluoro-3'-methylbiphenyl; 4-(4-Fluoro-3-methylphenyl)phenol; 64465-60-7; 4-Fluoro-3-methylbiphenyl-4'-ol
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-3'-Methyl-[1,1'-Biphenyl]-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.