Description

2-Chloro-5-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it a critical building block for creating molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group contributes to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in display technologies.
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The benzyl alcohol moiety can be functionalized, making it a valuable substrate in palladium-catalyzed cross-coupling reactions for complex molecule assembly.
• Chemical Research: A valuable reagent for academic and industrial research in medicinal chemistry and material science.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	64372-62-9
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	(2-Chloro-5-(trifluoromethyl)phenyl)methanol; α-(2-Chloro-α,α,α-trifluoro-p-tolyl)methanol; 2-Chloro-α,α,α-trifluoro-p-toluyl alcohol; 2-Chloro-α,α,α-trifluoro-p-tolylmethanol; 1-Chloro-4-(hydroxymethyl)-2-(trifluoromethyl)benzene; Benzyl alcohol, 2-chloro-5-(trifluoromethyl)-; 2-Chloro-5-trifluoromethylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.