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4-o-[2-Amino-6-[(Aminocarbonyl)Amino]-2,3,6-Trideoxy-α-D-Ribo-Hexopyranosyl]-6-o-(3-Amino-3-Deoxy-α-D-Glucopyranosyl)-2-Deoxy-D-Streptamine CAS NO 64332-35-0
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CAS No.:64332-35-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-o-[2-Amino-6-[(Aminocarbonyl)Amino]-2,3,6-Trideoxy-α-D-Ribo-Hexopyranosyl]-6-o-(3-Amino-3-Deoxy-α-D-Glucopyranosyl)-2-Deoxy-D-Streptamine is a complex aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key intermediate or reference standard for the synthesis and quality control of novel antibiotic agents and other therapeutic molecules. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of next-generation anti-infective drugs and biochemical studies.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathways for novel aminoglycoside antibiotics and related bioactive compounds.
- Biochemical Research: Used as a reference standard or probe in studies investigating bacterial ribosome function, antibiotic mechanisms of action, and resistance pathways.
- Analytical Standard: Essential for developing and validating analytical methods (e.g., HPLC, LC-MS) for the quantification and purity assessment of related drug substances.
- Medicinal Chemistry: Provides a core scaffold for structure-activity relationship (SAR) studies aimed at modifying pharmacological properties and reducing toxicity.
- Quality Control & Compliance: Employed by QC laboratories to ensure the identity, purity, and potency of bulk active pharmaceutical ingredients (APIs) within the aminoglycoside class.
Basic Information
| Product Name | 4-o-[2-Amino-6-[(Aminocarbonyl)Amino]-2,3,6-Trideoxy-α-D-Ribo-Hexopyranosyl]-6-o-(3-Amino-3-Deoxy-α-D-Glucopyranosyl)-2-Deoxy-D-Streptamine |
| CAS No. | 64332-35-0 |
| Molecular Formula | C20H38N6O11 |
| Molecular Weight | 538.55 g/mol |
| Synonyms | 2-Deoxy-4-O-(2-amino-6-[(aminocarbonyl)amino]-2,3,6-trideoxy-α-D-ribo-hexopyranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)streptamine; Paromamine derivative; 6'-N-Carbamoylparomamine; 4-O-(6'-N-Carbamoylparomamine)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxystreptamine; Aminoglycoside intermediate CAS 64332-35-0 |
| EINECS | Contact for details |
Quality Control
Our 4-o-[2-Amino-6-[(Aminocarbonyl)Amino]-2,3,6-Trideoxy-α-D-Ribo-Hexopyranosyl]-6-o-(3-Amino-3-Deoxy-α-D-Glucopyranosyl)-2-Deoxy-D-Streptamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
| Related Substances (HPLC) | Total impurities ≤ 3.0% Any single impurity ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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