Description

n-Acetyl-3-Hydroxy-L-Phenylalanine is a chemically modified derivative of the amino acid L-tyrosine, featuring an acetyl group and a phenolic hydroxyl group. This specific functionalization makes it a valuable chiral building block and intermediate for advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Biochemical Research: Used as a precursor or standard in studies of tyrosine metabolism, enzyme kinetics, and post-translational modifications like acetylation.
• Peptide Synthesis: Serves as a protected tyrosine analog in solid-phase and solution-phase peptide synthesis to introduce specific functional groups.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method development.
• Cosmetic Ingredient Research: Investigated for potential use in advanced skincare formulations due to its tyrosine-derived structure.
• Academic & Industrial R&D: A fundamental compound for organic synthesis projects and the development of new chemical entities in discovery chemistry.

Basic Information

Product Name	n-Acetyl-3-Hydroxy-L-Phenylalanine
CAS No.	64325-07-1
Molecular Formula	C11H13NO5
Molecular Weight	239.23 g/mol
Synonyms	N-Acetyl-L-tyrosine; N-Acetyltyrosine; Ac-Tyr-OH; (2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoic Acid; 3-(4-Hydroxyphenyl)-2-(acetylamino)propanoic Acid; L-Tyrosine, N-acetyl-; NSC 3346; Oxiracetam Impurity F (EP)
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Hydroxy-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in 1N HCl)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.