Description

Atracurium Besylate is a non-depolarizing neuromuscular blocking agent belonging to the benzylisoquinolinium class. It is a critical pharmaceutical intermediate and active pharmaceutical ingredient (API) used in the formulation of injectable anesthetic agents. This compound is essential for manufacturers in the pharmaceutical and biotechnology sectors requiring high-purity raw materials for sterile injectable production. Atracurium Besylate CAS NO 64228-81-5 is supplied under stringent quality controls to meet the exacting standards of modern pharmacopeias.

Application

• Primary Active Pharmaceutical Ingredient (API) in the manufacture of injectable neuromuscular blocking agents.
• Critical intermediate in the synthesis of besylate salt forms of pharmaceutical compounds.
• Used in research and development of new anesthetic and muscle relaxant formulations.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Component in non-depolarizing neuromuscular blocker studies within pharmacological research.
• Raw material for contract manufacturing organizations (CMOs) producing finished dosage forms.

Basic Information

Product Name	Atracurium Besylate
CAS No.	64228-81-5
Molecular Formula	C65H82N2O18S2
Molecular Weight	1243.5 g/mol
Synonyms	Atracurium Besilate; 2,2'-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] dibenzenesulfonate; 33A74; BW 33A; Tracrium (Brand Name); Atracurium Besylate API; (1R,1'R,2R,2'R)-2,2'-[Pentane-1,5-diylbis(oxy-3-oxopropane-3,1-diyl)]bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-ium) dibenzenesulfonate
EINECS	Contact for details

Quality Control

Our Atracurium Besylate is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance protocols are designed to comply with cGMP (current Good Manufacturing Practice) guidelines. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Specifications are aligned with major pharmacopeial standards, including USP and EP, where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Specific Rotation	Contact for details
Microbial Limits	Meets Ph. Eur. 2.6.12 & 2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.