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5-Methoxy-Pyrimidine-4-Carboxylic Acid Methyl Ester CAS NO 64224-66-4


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CAS No.:64224-66-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Methoxy-Pyrimidine-4-Carboxylic Acid Methyl Ester is a high-purity pyrimidine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

  • Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates.
  • Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
  • Chemical Synthesis: Serves as a versatile precursor for further functionalization, including hydrolysis to the corresponding acid or reactions at the methoxy and ester groups.
  • Material Science: Potential building block for specialty polymers, ligands for catalysis, or organic electronic materials.
  • Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name 5-Methoxy-Pyrimidine-4-Carboxylic Acid Methyl Ester
CAS No. 64224-66-4
Molecular Formula C8H10N2O3
Molecular Weight 182.18 g/mol
Synonyms Methyl 5-methoxypyrimidine-4-carboxylate; 4-Pyrimidinecarboxylic acid, 5-methoxy-, methyl ester; 5-Methoxy-4-pyrimidinecarboxylic acid methyl ester; Methyl 5-methoxy-4-pyrimidinecarboxylate; 5-Methoxypyrimidine-4-carboxylic acid methyl ester; 5-Methoxy-4-(methoxycarbonyl)pyrimidine
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Quality Control

Our 5-Methoxy-Pyrimidine-4-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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