Description

5-Chloropyrimidine-4-Carboxylic Acid is a versatile and high-purity pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized chloropyrimidine core, which enables precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile precursor in heterocyclic and medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science: Potential building block for the synthesis of specialty polymers, ligands, and functional organic materials.
• Custom Synthesis: Employed in contract research and manufacturing (CRAM) for bespoke chemical development projects.

Basic Information

Product Name	5-Chloropyrimidine-4-Carboxylic Acid
CAS No.	64224-65-3
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 5-chloro-; 5-Chloro-4-pyrimidinecarboxylic acid; 5-Chloropyrimidine-4-carboxylic acid; 5-Chloro-4-carboxypyrimidine; 5-Chloro-4-pyrimidine carboxylic acid; 5-Chloro-4-pyrimidinecarboxylate; 5-Chloro-4-carboxylic acid pyrimidine; 5-Chloro-4-pyrimidinecarboxylic acid (CAS 64224-65-3)
EINECS	Contact for details

Quality Control

Our 5-Chloropyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.