Description

Ethyl 5-Chloropyrimidine-4-Carboxylate is a versatile pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both an ester group and a halogenated heterocyclic core for selective derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine scaffold's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	Ethyl 5-Chloropyrimidine-4-Carboxylate
CAS No.	64224-64-2
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	5-Chloropyrimidine-4-carboxylic acid ethyl ester; Ethyl 5-chloro-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 5-chloro-, ethyl ester; 5-Chloro-4-pyrimidinecarboxylic acid ethyl ester; 64224-64-2; Ethyl 5-chloropyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloropyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.