Description

5-Bromo-4-Pyrimidinecarboxylic Acid is a versatile and high-value brominated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a key intermediate for the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of high-purity heterocyclic intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and anticancer compounds.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a functionalized scaffold for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation or as a core structure in designing molecular probes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Bromo-4-Pyrimidinecarboxylic Acid
CAS No.	64224-60-8
Molecular Formula	C5H3BrN2O2
Molecular Weight	202.99 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 5-bromo-; 5-Bromopyrimidine-4-carboxylic acid; 5-Bromo-4-carboxypyrimidine; 5-Bromo-4-pyrimidinecarboxylic acid; 5-Bromopyrimidine-4-carboxylic acid; 5-Bromo-4-pyrimidine carboxylic acid; 5-Bromo-4-pyrimidinecarboxylate; 5-Bromo-4-pyrimidinecarboxylic acid (CAS 64224-60-8)
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Pyrimidinecarboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment aligns with industry best practices for high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.