Description

Dl-Propargylglycine is a non-proteinogenic amino acid derivative featuring a reactive propargyl side chain. This compound serves as a versatile building block and a potent, irreversible inhibitor of enzymes like cystathionine γ-lyase (CSE), making it a critical tool for biochemical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors who require high-purity intermediates for drug discovery, metabolic pathway studies, and the synthesis of novel bioactive molecules.

Application

• Biochemical Research: A key inhibitor used to study the transsulfuration pathway, hydrogen sulfide (H₂S) biosynthesis, and related physiological processes.
• Pharmaceutical Intermediates: Serves as a crucial chiral synthon in the research and development of new therapeutic agents and prodrugs.
• Enzyme Inhibition Studies: Employed in vitro and in vivo to selectively inhibit cystathionine γ-lyase (CSE), aiding in the exploration of cardiovascular, neurological, and inflammatory diseases.
• Metabolic Pathway Analysis: Used as a tool compound to investigate amino acid metabolism and its role in cellular function and disease states.
• Agrochemical Research: Acts as a precursor or active component in the development of novel plant growth regulators or herbicides.
• Peptide Synthesis: Incorporated into synthetic peptides to introduce alkyne handles for bio-conjugation via click chemistry, enabling labeling and probing of biological systems.

Basic Information

Product Name	Dl-Propargylglycine
CAS No.	64165-64-6
Molecular Formula	C₅H₇NO₂
Molecular Weight	113.11 g/mol
Synonyms	2-Amino-4-pentynoic acid; (±)-Propargylglycine; DL-2-Amino-4-pentynoic acid; (RS)-2-Amino-4-pentynoic acid; 4-Pentynoic acid, 2-amino-; Propargylglycine (racemic); CSE Inhibitor; NSC 113671
EINECS	Contact for details

Quality Control

Our Dl-Propargylglycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade research standards. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.