Description

Lhrh, Gln(1)-Des-His(2)-Phe(6)-n-Et-Pronh2(9)- CAS NO 64153-06-6 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), specifically engineered as a potent antagonist. This compound is critical for advanced research and development in endocrinology and reproductive biology, offering a high degree of specificity for receptor binding studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents for hormone-dependent conditions.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel LHRH antagonist therapies.
• Endocrinology Studies: Used in vitro and in vivo to investigate the hypothalamic-pituitary-gonadal axis, receptor mechanisms, and hormone regulation.
• Preclinical Drug Evaluation: Essential for pharmacokinetic, pharmacodynamic, and toxicology studies of potential therapeutic candidates targeting hormone receptors.
• Biochemical Assay Development: Employed as a high-purity ligand in competitive binding assays, ELISA development, and other diagnostic research applications.
• Academic Research: Supports fundamental scientific investigations into peptide hormone action, signal transduction, and molecular biology.

Basic Information

Product Name	Lhrh, Gln(1)-Des-His(2)-Phe(6)-n-Et-Pronh2(9)- CAS NO 64153-06-6
CAS No.	64153-06-6
Molecular Formula	C58H78N16O12
Molecular Weight	1151.3 g/mol
Synonyms	LHRH Antagonist (Gln1, Des-His2, Phe6, N-Et-Pro-NH2(9)); Azaline B; [Ac-D-Nal1, D-Cpa2, D-Pal3, Arg5, D-Arg6, Leu7, N-Et-Pro9, D-Ala10]LHRH; Cetrorelix Analog; Gonadotropin-Releasing Hormone Antagonist; GnRH Antagonist Azaline B; (Des-His2, N-Et-Pro9)-LHRH
EINECS	Contact for details

Quality Control

Our Lhrh, Gln(1)-Des-His(2)-Phe(6)-n-Et-Pronh2(9)- CAS NO 64153-06-6 is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure consistent quality and batch-to-batch reproducibility. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, Acetic Acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.