Description

2α,3β-[[(3Ar,4S,7Ar)-7,7A-Dihydro-4H-1,3-Dioxolo[4,5-C]Pyran-3A,4(6H)-Diyl]Bis(Oxy)]-11α,14-Dihydroxy-12-Oxocarda-4,20(22)-Dienolide is a complex, high-purity cardenolide derivative with a specific stereochemical configuration. This compound is of significant interest for its potential as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily targeted at R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, structurally defined molecules for synthesis and biological evaluation.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathways for novel cardioactive steroids and other therapeutic agents.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and compound identification via HPLC, LC-MS, or NMR.
• Medicinal Chemistry Research: Provides a scaffold for structure-activity relationship (SAR) studies aimed at discovering new drugs with targeted biological activity.
• Biochemical Research: Employed in studies investigating the mechanism of action of cardenolides on sodium-potassium ATPase pumps and related cellular processes.
• Process Development: Used in the scale-up and optimization of synthetic routes for complex natural product derivatives within fine chemical manufacturing.

Basic Information

Product Name	2α,3β-[[(3Ar,4S,7Ar)-7,7A-Dihydro-4H-1,3-Dioxolo[4,5-C]Pyran-3A,4(6H)-Diyl]Bis(Oxy)]-11α,14-Dihydroxy-12-Oxocarda-4,20(22)-Dienolide
CAS No.	64144-98-5
Molecular Formula	C29H36O11
Molecular Weight	560.59 g/mol
Synonyms	12-Oxocarda-4,20(22)-dienolide, 2α,3β-[[(3aR,4S,7aR)-7,7a-dihydro-4H-1,3-dioxolo[4,5-c]pyran-3a,4(6H)-diyl]bis(oxy)]-11α,14-dihydroxy-; 2α,3β:11α,14-Bisepoxy-12-oxo-5β,14β-card-20(22)-enolide 2,3:11,12-bis(ethyl orthoacetate); Card-20(22)-enolide, 2,3:11,12-bis(ethyl orthoacetate)-12-oxo-5β,14β-; A derivative of digitoxigenin or strophanthidin.
EINECS	Contact for details

Quality Control

Our 2α,3β-[[(3Ar,4S,7Ar)-7,7A-Dihydro-4H-1,3-Dioxolo[4,5-C]Pyran-3A,4(6H)-Diyl]Bis(Oxy)]-11α,14-Dihydroxy-12-Oxocarda-4,20(22)-Dienolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.