Description

2-Phenyl-Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key synthon in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesis and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its pyrimidine core structure.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis projects.
• Academic Research: Used in university laboratories for methodological development and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	2-Phenyl-Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	64074-29-9
Molecular Formula	C13H12N2O2
Molecular Weight	228.25 g/mol
Synonyms	Methyl 2-phenylpyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-phenyl-, methyl ester; 2-Phenyl-5-pyrimidinecarboxylic acid methyl ester; Methyl 2-phenyl-5-pyrimidinecarboxylate; 2-Phenylpyrimidine-5-carboxylic acid methyl ester; 64074-29-9; Methyl 2-phenyl-1,3-diazine-5-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-Phenyl-Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.