Description

Spectinomycin Sulfate Tetrahydrate is a high-purity aminocyclitol antibiotic salt, primarily valued for its potent activity against a broad spectrum of Gram-negative and some Gram-positive bacteria. Its significance lies in its specialized use as a key active pharmaceutical ingredient (API) and a critical reagent in microbiological research and veterinary medicine. This product is essential for manufacturers in the pharmaceutical, veterinary drug, and life science research industries, where reliable quality and consistent biological activity are paramount.

Application

• Active Pharmaceutical Ingredient (API): Core component in the formulation of human and veterinary antibiotic injections and solutions.
• Veterinary Medicine: Used in treatments for bacterial infections in livestock, poultry, and companion animals.
• Microbiological Research: Serves as a selective agent in culture media for the isolation and study of resistant bacterial strains.
• Cell Culture & Molecular Biology: Employed as an antibiotic supplement in cell culture systems to prevent bacterial contamination.
• Reference Standard: Used in analytical laboratories for quality control and method validation via HPLC or other chromatographic techniques.
• Intermediate for Synthesis: Acts as a starting material or intermediate for the synthesis of more complex antibiotic derivatives.

Basic Information

Product Name	Spectinomycin Sulfate Tetrahydrate
CAS No.	64058-48-6
Molecular Formula	C14H28N2O11·H2SO4·4H2O
Molecular Weight	540.53 g/mol (Tetrahydrate)
Synonyms	Spectinomycin Sulfate Hydrate; Spectinomycin Hemisulfate Tetrahydrate; Actinospectacin Sulfate; Trobicin (Brand Name); U-18409; Antibiotic U-18409; Spectam; (1R,2S,5R,6R,7S,8R,9S,10R)-4,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one Sulfate
EINECS	Contact for details

Quality Control

Our Spectinomycin Sulfate Tetrahydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with industry expectations for pharmaceutical-grade materials. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
pH (1% solution)	3.5 - 5.5
Water Content (KF)	11.0% - 14.0% (Theoretical for Tetrahydrate: ~13.3%)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.25 EU/mg (if applicable)
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.