Description

1-[2-(Aminocarbonyloxy)-3-Isopropoxypropyl]-5-Ethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its specific heterocyclic structure, which serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents and other specialized therapeutic compounds. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of barbiturate-derived active pharmaceutical ingredients (APIs) and other neuroactive compounds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Process Chemistry: Serves as a building block in the development and optimization of scalable synthetic routes for target molecules.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Synthesis: Utilized in organic synthesis to introduce specific functionalized pyrimidinetrione moieties into more complex molecular architectures.

Basic Information

Product Name	1-[2-(Aminocarbonyloxy)-3-Isopropoxypropyl]-5-Ethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	64038-12-6
Molecular Formula	C19H25N3O6
Molecular Weight	391.42 g/mol
Synonyms	5-Ethyl-5-phenyl-1-[2-(ureidooxy)-3-isopropoxypropyl]barbituric acid; 1-[2-(Carbamoyloxy)-3-isopropoxypropyl]-5-ethyl-5-phenylbarbituric acid; 1-[2-(Aminocarbonyloxy)-3-isopropoxypropyl]-5-ethyl-5-phenylbarbituric acid; APoB; Aprobarbital derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-[2-(Aminocarbonyloxy)-3-Isopropoxypropyl]-5-Ethyl-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.