Description

Kanamycin Acid Sulfate is a water-soluble, semi-synthetic aminoglycoside antibiotic derived from *Streptomyces kanamyceticus*. This compound is critical for its potent bactericidal activity against a broad spectrum of Gram-negative and some Gram-positive bacteria. It is an essential raw material and intermediate for the pharmaceutical industry, particularly in the formulation of injectable antibiotics and in microbiological research. Kanamycin Acid Sulfate CAS NO 64013-70-3 is supplied as a high-purity, off-white to white powder suitable for demanding applications.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Primary use as a key intermediate in the synthesis of kanamycin sulfate injections and other antibiotic formulations.
• Microbiological Research & Cell Culture: Used as a selective agent in cell culture media to prevent bacterial contamination.
• Veterinary Medicine: Employed in the development of treatments for bacterial infections in livestock and companion animals.
• Molecular Biology: Serves as a selection marker in genetic engineering and plasmid construction for recombinant DNA work.
• Diagnostic Reagents: A component in certain diagnostic kits and agars for bacterial identification and susceptibility testing.
• Biochemical Synthesis: Acts as a starting material or intermediate for the synthesis of more complex aminoglycoside derivatives.

Basic Information

Product Name	Kanamycin Acid Sulfate
CAS No.	64013-70-3
Molecular Formula	C18H36N4O11 • H2SO4
Molecular Weight	582.58 g/mol (for free base, as kanamycin)
Synonyms	Kanamycin Monosulfate; Kanamycin A Sulfate; Kanamycin Sulfate (Acid); Kanamycin Sulphate; Kantrex (trade name basis); 6-O-(3-Amino-3-deoxy-α-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine Sulfate; NSC-132679
EINECS	Contact for details

Quality Control

Our Kanamycin Acid Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research use. A Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, purity, identification, and impurity profiles. We adhere to cGMP principles where applicable, and the product can be supplied to meet various pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
pH (1% Solution)	6.0 - 8.0
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	+112° to +123°
Bacterial Endotoxins	< 0.25 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.